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To do that, the game would have to break the following security barriers:

• Run as admin
• Bypass Anti-Virus without being detected.
• Gain access to Ring 0 for direct hardware IO
• Wipe the volatile BIOS storage

Conclusion: Your BIOS battery died and the settings got deleted. Most of the BIOS batteries are lithium, so they hold their voltage until they are truely dead/end of life.

Just buy a new coin cell, you can get in any store for $1-2.

Ok, it must be something with my Windows 10 installation. 

Out of curiosity, I slapped the game in a "Windows XP x64" Virtual Machine and it runs perfectly fine in there. I could even save. 

Very weird. Welp, gonna play in a VM then.

Sorry for the late answer. Here you go.

Works normally. Are you using javascript blockers (f.e ScriptSafe on Chrome?) in your browser? 

It gives me an MVC++ Runtime error after the question "what is your name" - "lets get to know each other better. it crashes on "how her house was", if you do the exact same talk twice in a row. If you want i can make a video to show it to you.

The game crashes unexpectedly during the "Talk" section after I give her/it my name, any way to temporary fix it?

Open game, press Alt+Enter. Pretty oldschool, but works.